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Home / Primary Antibodies / Polyclonal Antibodies

Anti-FMO1 Antibody Picoband®

SKU : BHA21000485

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Mfr.No.	PB9589, PB9589-10ug, PB9589-Biotin, PB9589-Cy3, PB9589-Dylight488, PB9589-Dylight550, PB9589-Dylight594, PB9589-FITC, PB9589-HRP, PB9589-APC, PB9589-PE, PB9589-iFluor647, PB9589-carrier-free
Alternative Names	Dimethylaniline monooxygenase (N-oxide-forming) 1
Background	Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-FMO1 Antibody Picoband® catalog # PB9589. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human FMO1, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	60 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Dimethylaniline monooxygenase (N-oxide-forming) 1;1.14.13.8;Dimethylaniline oxidase 1;Fetal hepatic flavin-containing monooxygenase 1;FMO 1;FMO1;
Tissue Specificity	Expressed mainly in fetal liver, adult kidney and, to a lesser extent, the intestine.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q01740
Gene Id	2326
Gene Name	FMO1
Sequence	Belongs to the FMO family.
Subcellular Location	Microsome membrane. Endoplasmic reticulum membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat

Reference	1. "Entrez Gene: FMO1 flavin containing monooxygenase 1". 2. Cashman JR (2004). "The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development".Drug Discov. Today 9 (13): 574581. 3. Dolphin C, Shephard EA, Povey S et al. (1991). "Cloning, primary sequence, and chromosomal mapping of a human flavin-containing monooxygenase (FMO1)".J. Biol. Chem. 266 (19): 1237985.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000485-1	PB9589	100 ug	-	$370		Add to Cart
BHA21000485-2	PB9589-10ug	10 ug	Sample	$99		Add to Cart
BHA21000485-3	PB9589-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000485-4	PB9589-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000485-5	PB9589-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000485-6	PB9589-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000485-7	PB9589-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000485-8	PB9589-FITC	100 ug	FITC	$570		Add to Cart
BHA21000485-9	PB9589-HRP	100 ug	HRP	$570		Add to Cart
BHA21000485-10	PB9589-APC	100 ug	APC	$670		Add to Cart
BHA21000485-11	PB9589-PE	100 ug	PE	$670		Add to Cart
BHA21000485-12	PB9589-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000485-13	PB9589-carrier-free	100 ug	carrier-free	$370		Add to Cart

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