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Home / Primary Antibodies / Polyclonal Antibodies

Anti-FGF8 Antibody Picoband®

SKU : BHA21001304

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Mfr.No.	A00841, A00841-10ug, A00841-Biotin, A00841-Cy3, A00841-Dylight488, A00841-Dylight550, A00841-Dylight594, A00841-FITC, A00841-HRP, A00841-APC, A00841-PE, A00841-iFluor647, A00841-carrier-free
Alternative Names	fibroblast growth factor 8
Background	Fibroblast growth factor 8 (androgen-induced), also known as FGF8 or AIGF, is a human gene which maps to 10q24. The protein encoded by this gene is secreted proteins that interact with FGF tyrosine kinase receptors to mediate growth and development. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The temporal and spatial pattes of this gene expression suggest that FGF8 is involved in gastrulation, regionalization of the brain, and organogenesis of the limb and face as an embryonic epithelial factor. The adult expression of FGF8 is restricted to gonads, including testes and ovaries. FGF8 stimulated growth of human prostate carcinoma cells and mouse fibroblasts and mammary carcinoma cells in a dose-dependent manner. It also may play an important role in growth and patteing of limbs, face, and central nervous system. FGF8 is expressed in increased levels in breast cancer and in lactating human breast; it was also detected in human milk. A survey of other normal tissues showed that FGF8 is expressed in the proliferative cells of the skin and epithelial cells in colon, ovary, fallopian tube, and uterus.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-FGF8 Antibody Picoband® catalog # A00841. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotr
Host	Rabbit
Immunogen Region	E. coli-derived human FGF8 recombinant protein (Position: Q23-R233).
Isotype	Rabbit IgG
Molecular Weight	26 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Fibroblast growth factor 8; FGF-8; Androgen-induced growth factor; AIGF; Heparin-binding growth factor 8; HBGF-8; FGF8; AIGF;
Tissue Specificity	Widely expressed.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	FGF8: P55075
Gene Id	2253
Gene Name	FGF8
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.1-0.5ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Tanaka, A.; Miyamoto, K.; Matsuo, H.; Matsumoto, K.; Yoshida, H. : Human androgen-induced growth factor in prostate and breast cancer cells: its molecular cloning and growth properties. FEBS Lett. 363: 226-230, 1995.<br /><br />2. Yoshiura, K.; Leysens, N. J.; Chang, J.; Ward, D.; Murray, J. C.; Muenke, M. : Genomic structure, sequence, and mapping of human FGF8 with no evidence for its role in craniosynostosis/limb defect syndromes. Am. J. Med. Genet. 72: 354-362, 1997.<br /><br />3. Zammit, C.; Coope, R.; Gomm, J. J.; Shousha, S.; Johnston, C. L.; Coombes, R. C. : Fibroblast growth factor 8 is expressed at higher levels in lactating human breast and in breast cancer. Brit. J. Cancer 86: 1097-1103, 2002.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001304-1	A00841	100 ug	-	$370		Add to Cart
BHA21001304-2	A00841-10ug	10 ug	Sample	$99		Add to Cart
BHA21001304-3	A00841-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001304-4	A00841-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001304-5	A00841-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001304-6	A00841-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001304-7	A00841-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001304-8	A00841-FITC	100 ug	FITC	$570		Add to Cart
BHA21001304-9	A00841-HRP	100 ug	HRP	$570		Add to Cart
BHA21001304-10	A00841-APC	100 ug	APC	$670		Add to Cart
BHA21001304-11	A00841-PE	100 ug	PE	$670		Add to Cart
BHA21001304-12	A00841-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001304-13	A00841-carrier-free	100 ug	carrier-free	$370		Add to Cart

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