Epithelial Membrane Antigen (EMA) is a mucin glycoprotein expressed on apical epithelial cells. Anti-EMA positively stains normal and neoplastic cells including sweat glands, mammary epithelia, and squamous epithelia. Adrenal carcinoma, seminomas, paraganglioma, hepatocellular carcinoma, and embryonal carcinomas exhibit a negative stain. As Anti-EMA commonly reacts positively with meningioma, it is useful for differentiating this tumour from other intracranial neoplasms such as schwannomas.
Host
Mouse
Isotype
IgG2a
Species
Human
Clone No
IHC566
Buffer
Tris Buffer pH7.6 with BSA, and sodium azide as preservative