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Home / Primary Antibodies / IHC Antibodies

Anti-CYP2C19/CYP2C9/CYP2C8/CYP2C18 Antibody BHA11301208

SKU : BHA11301208

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Mfr.No.	BS2195
Alternative Names	Cytochrome P450 2C9 ; (R)-limonene 6-monooxygenase ; (S)-limonene 6-monooxygenase ; (S)-limonene 7-monooxygenase ; CYPIIC9 ; Cytochrome P-450MP ; Cytochrome P450 MP-4 ; Cytochrome P450 MP-8 ; Cytochrome P450 PB-1 ; S-mephenytoin 4-hydroxylase ; CYP2C9 ; CYP2C10 ; Cytochrome P450 2C8 ; CYPIIC8 ; Cytochrome P450 IIC2 ; Cytochrome P450 MP-12 ; Cytochrome P450 MP-20 ; Cytochrome P450 form 1 ; S-mephenytoin 4-hydroxylase ; CYP2C8 ; Cytochrome P450 2C18 ; CYPIIC18 ; Cytochrome P450-6b/29c ; CYP2C18 ; Cytochrome P450 2C19 ; (R)-limonene 6-monooxygenase ; (S)-limonene 6-monooxygenase ; (S)-limonene 7-monooxygenase ; CYPIIC17 ; CYPIIC19 ; Cytochrome P450-11A ; Cytochrome P450-254C ; Mephenytoin 4-hydroxylase ; CYP2C19
Antigen	CYP2C19/CYP2C9/CYP2C8/CYP2C18
Categories	Primary Antibodies
Clonality	polyclonal
Description	The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP2C (CYPIIC) subfamily comprises a group of constitutively expressed genes, some phenobarbital-induced genes, and several genes associated with sex-specific expression. Originally, at least 7 genes were assigned to the CYP2C subfamily, which maps to human 10q24.1-q24.3 and mouse chromosome 19. Humans contain fewer genes in this cluster than do mice or rats. Four genes are arranged in the following order and orientation along human chromosome 10: RBP4, CYP2C18, CYP2C19/CYP2C9, and CYP2C8. The previsously identified CYP2C10 is an artifact of CYP2C9 and not a distinct isoform. All of the CYP2C proteins localize to the endoplasmic reticulum.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 100-150 of Human CYP2C8.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P33260/P10632/P11712/P33261
Uniprot	P33260/P10632/P11712/P33261
Weight	60 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: CYP2C8/9/18/19 (M136) polyclonal antibody detects endogenous levels of CYP2C8/9/18/19 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IF

Description

IHC ; IF

Dilution

IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301208	BS2195	50µl	$190.44		Add to Cart
BHA11301208	BS2195	100µl	$294.44		Add to Cart

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