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Home / Primary Antibodies / IHC Antibodies

Anti-CSTF2 Antibody BHA11301067

SKU : BHA11301067

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Mfr.No.	BS1980
Alternative Names	Cleavage stimulation factor 64 kDa subunit ; CSTF 64 kDa subunit ; CF-1 64 kDa subunit ; CstF64 ; CstF 64 ; CSTF2
Categories	Primary Antibodies
Chromosome Location	Xq22.1
Clonality	polyclonal
Description	CstF-64 contains an RNA binding domain and is responsible for the RNA binding activity of CstF. CstF-64 is expressed in all somatic cells and in pre- and postmeiotic, but not meiotic, germ cells. However, a large variant of CstF-64, called t CstF-64, is abundantly expressed in meiotic and postmeiotic cells in the testis and to a lesser extent in the brain, and promotes the germ cell pattern of polyadenylation. The gene encoding CstF-64 (designated CSTF2) maps to the X chromosome, whereas t CstF-64 is encoded by an autosomal gene. The increase in CstF-64 concentration during B cell activation switches IgM heavy chain mRNA expression from membrane-bound to secreted forms, suggesting that CstF-64 plays a key role in regulating IgM heavy chain expression during B cell differentiation.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids N-terminus of Human CstF-64.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P33240
Uniprot	P33240
Weight	64 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: CstF-64 (R46) polyclonal antibody detects endogenous levels of CstF-64 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301067	BS1980	50µl	$190.44		Add to Cart
BHA11301067	BS1980	100µl	$294.44		Add to Cart

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