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Home / Primary Antibodies / IHC Antibodies

Anti-CSE1L Antibody BHA11300262

SKU : BHA11300262

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Mfr.No.	BS1080
Alternative Names	Exportin 2 ; Exportin2 ; Exportin-2 ; Exp2 ; Cellular apoptosis susceptibility protein ; Chromosome segregation 1-like protein ; Importin-alpha re-exporter ; CSE1L ; CAS ; XPO2
Antigen	CSE1L
Categories	Primary Antibodies
Chromosome Location	20q13.13
Clonality	polyclonal
Description	Normal tissues are characterized by a balance between cellular stasis, cell proliferation, cell differentiation and cell death. Aberrant regulation of any of these cell processes can result in cancer. Cell death during embryogenesis, tissue atrophy and normal tissue turnover is called apoptosis. This is characterized by cytoplasmic and nuclear condensation, nuclear disorganization and fragmentation of genomic DNA into 180-200 base pair oligomers. Several human cDNA fragments have been shown to render MCF-7 cells resistant to cell death induced by Pseudomonas exotoxin, Pseudomonas exotoxin-derived immunotoxins, diptheria toxin and tumor necrosis factor (TNF). One such fragment has proven to be the human homolog to the yeast chromosome segregation homolog, CSE1. Cloning of the full-length human cDNA has revealed a putative protein designated CAS, for cellular apoptosis susceptibility, that is 971 amino acids in length with 59% overall sequence homology as compared to yeast CSE1. CAS is highly expressed in testis and fetal liver.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids N-terminus of Human CSE1L.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P55060
Uniprot	P55060
Weight	110 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: CSE1L (E2) polyclonal antibody detects endogenous levels of Exportin-2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IP, IF

Description

WB ; IHC ; IP ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IP	1:50-1:200
IF	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300262	BS1080	50µl	$190.44		Add to Cart
BHA11300262	BS1080	100µl	$294.44		Add to Cart

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