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Home / Primary Antibodies / Recombinant Antibodies

Anti-CRAT Antibody BHA11308071

SKU : BHA11308071

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Mfr.No.	BS8160
Alternative Names	Carnitine O-acetyltransferase ; Carnitine acetylase ; Carnitine acetyltransferase ; CAT ; CrAT ; CRAT ; CAT1
Antigen	CRAT
Categories	Primary Antibodies
Chromosome Location	9q34.11
Clonality	polyclonal
Description	Aging affects oxidative metabolism in liver and other tissues. Carnitine acyltransferases are key enzymes of this process in mitochondria. Carnitine acetyltransferase (CAT, CRAT) catalyzes the reversible conversion of acetyl-CoA and carnitine to acetylcarnitine and CoA. The essential functions of CAT are to regenerate CoA, which allows peroxisomal b-oxidation to proceed, and to facilitate transport of acetyl moieties to mitochondria for oxidation. More than 70% of CAT is located in the mitochondrial matrix and it is also located in the endoplasmic reticulum, peroxisomal and mitochondrial inner membrane. An age associated decrease in CAT activity has been reported in many rat systems. The human gene encoding CAT maps to chromosome 9q34.1 and encodes a protein that contains a peroxisomal targeting signal and is expressed mostly in skeletal muscle, and less in heart, liver and pancreas. Total CAT activity is induced by acetate and fatty acids, and repressed by glucose.
Host	Rabbit
Immunogen	Recombinant full length Human CRAT.
Reactivity	Human, Mouse
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P43155
Uniprot	P43155
Weight	60 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: CRAT polyclonal antibody detects endogenous levels of CRAT protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308071	BS8160	50µl	$234.89		Add to Cart
BHA11308071	BS8160	100µl	$368.22		Add to Cart

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