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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Cortisol Binding Globulin/SERPINA6 Antibody Picoband®

SKU : BHA21007412

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Mfr.No.	PA2230, PA2230-10ug, PA2230-Biotin, PA2230-Cy3, PA2230-Dylight488, PA2230-Dylight550, PA2230-Dylight594, PA2230-FITC, PA2230-HRP, PA2230-APC, PA2230-PE, PA2230-iFluor647, PA2230-carrier-free
Alternative Names	Corticosteroid-binding globulin
Background	Corticosteroid-binding globulin (CBG), also known as Serpin A6 is a protein that in humans is encoded by the SERPINA6 gene. It is mapped 14q32.13. This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Cortisol Binding Globulin/SERPINA6 Antibody catalog # PA2230. Tested in IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human Cortisol Binding Globulin.
Isotype	Rabbit IgG
Molecular Weight	60 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Corticosteroid-binding globulin;CBG;Serpin A6;Transcortin;SERPINA6;CBG;
Tissue Specificity	Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P08185
Gene Name	SERPINA6
Sequence	Belongs to the serpin family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, ICC, WB
Description	Immunocytochemistry , 0.5-1ug/ml, Human<br>Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br>Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Buss, C., Schuelter, U., Hesse, J., Moser, D., Phillips, D. I., Hellhammer, D., Meyer, J. Haploinsufficiency of the SEPRINA6 gene is associated with severe muscle fatigue: a de novo mutation in corticosteroid-binding globulin deficiency. J. Neural Transm. 114: 563-569, 2007.<br /><br />2. Torpy, D. J., Bachmann, A. W., Grice, J. E., Fitzgerald, S. P., Phillips, P. J., Whitworth, J. A., Jackson, R. V. Familial corticosteroid-binding globulin deficiency due to a novel null mutation: association with fatigue and relative hypotension. J. Clin. Endocr. Metab. 86: 3692-3700, 2001.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007412-1	PA2230	-	100 ug	$370		Add to Cart
BHA21007412-2	PA2230-10ug	Sample	10 ug	$99		Add to Cart
BHA21007412-3	PA2230-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007412-4	PA2230-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007412-5	PA2230-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007412-6	PA2230-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007412-7	PA2230-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007412-8	PA2230-FITC	FITC	100 ug	$570		Add to Cart
BHA21007412-9	PA2230-HRP	HRP	100 ug	$570		Add to Cart
BHA21007412-10	PA2230-APC	APC	100 ug	$670		Add to Cart
BHA21007412-11	PA2230-PE	PE	100 ug	$670		Add to Cart
BHA21007412-12	PA2230-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007412-13	PA2230-carrier-free	carrier-free	100 ug	$370		Add to Cart

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