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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CD34 Antibody Picoband®

SKU : BHA21006724

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Mfr.No.	PA1334, PA1334-10ug, PA1334-Biotin, PA1334-Cy3, PA1334-Dylight488, PA1334-Dylight550, PA1334-Dylight594, PA1334-FITC, PA1334-HRP, PA1334-APC, PA1334-PE, PA1334-iFluor647, PA1334-carrier-free
Alternative Names	Hematopoietic progenitor cell antigen CD34
Background	CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 KD.CD34 is expressed in humans in hematopoietic stem cells, vascular endothelium, and blasts from 30% of patients with acute myeloid and lymphocytic leukemia. The human CD34 gene spans 26 kb and has 8 exons, a structure quite similar to that of the murine gene. By Southe blot analysis of DNA from a panel of human x mouse somatic cell hybrids using a CD34 cDNA probe demonstrate that the gene for CD34 is located on human chromosome 1 in the 1q12----qter region. CD34 plays an important role in the formation of progenitor cells during both embryonic and adult hematopoiesis.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-CD34 Antibody catalog # PA1334. Tested in Flow Cytometry, IHC, IHC-F, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or ly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem c
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human CD34, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	105 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Hematopoietic progenitor cell antigen CD34;CD34;CD34;
Tissue Specificity	Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.01mg NaN3.

Uniprot	P28906
Gene Name	CD34
Sequence	Belongs to the CD34 family.
Subcellular Location	Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IHC, IHC-F, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Mouse, Rat, By Heat<br> Immunohistochemistry (Frozen Section), 0.5-1ug/ml, Mouse, Rat, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Satterthwaite, A. B., Bu, T. C., Le Beau, M. M., Tenen, D. G. Structure of the gene encoding CD34, a human hematopoietic stem cell antigen. Genomics 12: 788-794, 1992. <br /><br />2. Tenen, D. G., Satterthwaite, A. B., Borson, R., Simmons, D., Eddy, R. L., Shows, T. B. Chromosome 1 localization of the gene for CD34, a surface antigen of human stem cells. Cytogenet. Cell Genet. 53: 55-57, 1990.<br /><br />3. Cheng, J., Baumhueter, S., Cacalano, G., Carver-Moore, K., Thibodeaux, H., Thomas, R., Broxmeyer, H. E., Cooper, S., Hague, N., Moore, M., Lasky, L. A. Hematopoietic defects in mice lacking the sialomucin CD34. Blood 87: 479-490, 1996.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006724-1	PA1334	-	100 ug	$370		Add to Cart
BHA21006724-2	PA1334-10ug	Sample	10 ug	$99		Add to Cart
BHA21006724-3	PA1334-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006724-4	PA1334-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006724-5	PA1334-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006724-6	PA1334-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006724-7	PA1334-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006724-8	PA1334-FITC	FITC	100 ug	$570		Add to Cart
BHA21006724-9	PA1334-HRP	HRP	100 ug	$570		Add to Cart
BHA21006724-10	PA1334-APC	APC	100 ug	$670		Add to Cart
BHA21006724-11	PA1334-PE	PE	100 ug	$670		Add to Cart
BHA21006724-12	PA1334-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006724-13	PA1334-carrier-free	carrier-free	100 ug	$370		Add to Cart

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