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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CD20/MS4A1 Antibody Picoband®

SKU : BHA21007510

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Mfr.No.	PB9050, PB9050-10ug, PB9050-Biotin, PB9050-Cy3, PB9050-Dylight488, PB9050-Dylight550, PB9050-Dylight594, PB9050-FITC, PB9050-HRP, PB9050-APC, PB9050-PE, PB9050-iFluor647, PB9050-carrier-free
Alternative Names	B-lymphocyte antigen CD20
Background	CD20, also known as MS4A1, is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. It is mapped to 11q12.2. This gene encodes a member of the membrane-spanning 4A gene family. The function of CD20 is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that CD20 acts as a calcium channel in the cell membrane. What s more, this protein may be involved in the regulation of B-cell activation and proliferation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-CD20/MS4A1 Antibody Picoband® catalog # PB9050. Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	This protein may be involved in the regulation of B-cell activation and proliferation.
Host	Rabbit
Immunogen Region	E.coli-derived human CD20 recombinant protein (Position: M1-D261). Human CD20 shares 75% amino acid (aa) sequence identity with mouse CD20.
Isotype	Rabbit IgG
Molecular Weight	35 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	B-lymphocyte antigen CD20;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1;CD20;MS4A1;CD20;
Tissue Specificity	Expressed on B-cells.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P11836
Gene Id	931
Gene Name	MS4A1
Sequence	Belongs to the MS4A family.
Subcellular Location	Cell membrane ; Multi-pass membrane protein . Cell membrane ; Lipid-anchor .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, IHC-F, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, By Heat Immunohistochemistry (Frozen Section), 0.5-1ug/ml Immunocytochemistry, 0.5-1ug/ml Immunofluorescence, 2ug/ml, Human Flow Cytometry (Fixed), 1-3ug/1x10⁶cells

Reference	1. Cragg MS, Walshe CA, Ivanov AO, Glennie MJ (2005). "The biology of CD20 and its potential as a target for mAb therapy". Curr. Dir. Autoimmun. Current ions in Autoimmunity 8: 14074. 2. Hardy, Richard (2008). "Chapter 7: B Lymphocyte Development and Biology". In Paul, William.Fundamental Immunology (Book) (6th ed.). Philadelphia: Lippincott Williams & Wilkins. pp. 237269. 3. Kuijpers TW, Bende RJ, Baars PA, Grummels A, Derks IA, Dolman KM, Beaumont T, Tedder TF, van Noesel CJ, Eldering E, van Lier RA (January 2010). "CD20 deficiency in humans results in impaired T cell-independent antibody responses". J. Clin. Invest. 120 (1): 21422.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007510-1	PB9050	-	100 ug	$370		Add to Cart
BHA21007510-2	PB9050-10ug	Sample	10 ug	$99		Add to Cart
BHA21007510-3	PB9050-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007510-4	PB9050-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007510-5	PB9050-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007510-6	PB9050-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007510-7	PB9050-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007510-8	PB9050-FITC	FITC	100 ug	$570		Add to Cart
BHA21007510-9	PB9050-HRP	HRP	100 ug	$570		Add to Cart
BHA21007510-10	PB9050-APC	APC	100 ug	$670		Add to Cart
BHA21007510-11	PB9050-PE	PE	100 ug	$670		Add to Cart
BHA21007510-12	PB9050-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007510-13	PB9050-carrier-free	carrier-free	100 ug	$370		Add to Cart

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