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Home / Primary Antibodies / Polyclonal Antibodies

Anti-cardiac Troponin C/TNNC1 Antibody Picoband®

SKU : BHA21007047

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Mfr.No.	PA1779, PA1779-10ug, PA1779-Biotin, PA1779-Cy3, PA1779-Dylight488, PA1779-Dylight550, PA1779-Dylight594, PA1779-FITC, PA1779-HRP, PA1779-APC, PA1779-PE, PA1779-iFluor647, PA1779-carrier-free
Alternative Names	Troponin C, slow skeletal and cardiac muscles
Background	Troponin C1 (TNNC1) (troponin C type 1 (slow)), also called TROPONIN C, SLOW-TWITCH SKELETAL MUSCLE or TNC, is a protein that in humans is encoded by the TNNC1 gene. Using a "monochromosomal" hybrid panel, the TNNC1 gene is mapped to chromosome 3; subsequent analysis of the Genebridge 4 radiation hybrid panel localized the gene to 3p in a region consistent with the earlier assignment. Circular dichroism measurements revealed changes in the secondary structures of the TNNC1 mutants A8V, C84Y, and D145E.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-cardiac Troponin C/TNNC1 Antibody catalog # PA1779. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abo
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human cardiac Troponin C, identical to the related rat and mouse sequences .
Isotype	Rabbit IgG
Molecular Weight	18 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Troponin C, slow skeletal and cardiac muscles;TN-C;TNNC1;TNNC;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P63316
Gene Name	TNNC1
Sequence	Belongs to the troponin C family.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, Mouse, By Heat<br>Weste blot, 0.1-0.5ug/ml, Rat, Human, Mouse<br>

Reference	1. Bermingham, N., Heandez, D., Balfour, A., Gilmour, F., Martin, J. E., Fisher, E. M. C. Mapping TNNC1, the gene that encodes cardiac troponin I in the human and mouse. Genomics 30: 620-622, 1995.<br /><br />2. Hoffmann, B., Schmidt-Traub, H., Perrot, A., Osterziel, K. J., Gessner, R. First mutation in cardiac troponin C, L29Q, in a patient with hypertrophic cardiomyopathy. Hum. Mutat. 17: 524 only, 2001. <br /><br />3. Landstrom, A. P., Parvatiyar, M. S., Pinto, J. R., Marquardt, M. L., Bos, J. M., Tester, D. J., Ommen, S. R., Potter, J. D., Ackerman, M. J.Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin C. J. Molec. Cell. Cardiol. 45: 281-288, 2008.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007047-1	PA1779	-	100 ug	$370		Add to Cart
BHA21007047-2	PA1779-10ug	Sample	10 ug	$99		Add to Cart
BHA21007047-3	PA1779-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007047-4	PA1779-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007047-5	PA1779-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007047-6	PA1779-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007047-7	PA1779-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007047-8	PA1779-FITC	FITC	100 ug	$570		Add to Cart
BHA21007047-9	PA1779-HRP	HRP	100 ug	$570		Add to Cart
BHA21007047-10	PA1779-APC	APC	100 ug	$670		Add to Cart
BHA21007047-11	PA1779-PE	PE	100 ug	$670		Add to Cart
BHA21007047-12	PA1779-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007047-13	PA1779-carrier-free	carrier-free	100 ug	$370		Add to Cart

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