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Home / Primary Antibodies / Recombinant Antibodies

Anti-CAMK1 Antibody BHA11308457

SKU : BHA11308457

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Mfr.No.	BS8651
Alternative Names	CaM K1 ; CaM KI ; CaM kinase 1 alpha ; CAM kinase 1 ; CaM kinase I alpha ; CAM kinase I ; CaMK 1 ; CAMK I ; CaMK1 alpha ; CaMK1 ; CAMK1 PEN ; CaMKI alpha ; MGC120317 ; MGC120318
Antigen	CAMK1
Categories	Primary Antibodies
Chromosome Location	3p25.3
Clonality	polyclonal
Description	The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated α, β, γ and δ, which may or may not be coexpressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation. Stimulation of the T cell receptor CD3 signaling complex with an anti-CD3 monoclonal, leads to a 10-40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory threonine residue at position 177.
Host	Rabbit
Immunogen	Recombinant full length Human CaMKIα.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q14012
Uniprot	Q14012
Weight	41kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: CaMKIα polyclonal antibody detects endogenous levels of CaMKIα protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308457	BS8651	50µl	$234.89		Add to Cart
BHA11308457	BS8651	100µl	$368.22		Add to Cart

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