This antibody recognizes human BTLA. It has not been tested with other species.
Description
This anti-BTLA antibody is a purified recombinant human monoclonal antibody which recognizes the human BTLA protein. BTLA (B- and T-lymphocyte attenuator) belongs to the CD28 immunoglobulin superfamily (IgSF) and is an immune-regulatory receptor that binds to HVEM (Herpesvirus entry mediator, also known as TNFRSF14, Tumor necrosis factor receptor superfamily member 14). This antibody has been tested for specific binding to purified human BTLA protein and neutralizes the interaction between BTLA and HVEM.
assay conditions: See datasheet for detailed information
Formulation
8 mM phosphate, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Isotype
IgG1
Molecular Weight
150 kDa
Species
Human
Synonyms
BTLA1, B and T lymphocyte associated, B- and T-lymphocyte attenuator, CD272
Note
Avoid freeze/thaw cycles.
Format
Aqueous buffer solution
Purification
Protein A affinity chromatography from HEK293 supernatants