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Home / Primary Antibodies / Recombinant Antibodies

Anti-BIRC2 Antibody BHA11303970

SKU : BHA11303970

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Mfr.No.	BS6088
Alternative Names	Baculoviral IAP repeat-containing protein 2 ; C-IAP1 ; IAP homolog B ; Inhibitor of apoptosis protein 2 ; IAP-2 ; hIAP-2 ; hIAP2 ; RING finger protein 48 ; TNFR2-TRAF-signaling complex protein 2 ; API1 ; IAP2 ; MIHB ; RNF48
Categories	Primary Antibodies
Chromosome Location	11q22.2
Clonality	polyclonal
Description	Three mammalian homologs of baculovirus p35, designated MIHA (mammalian IAP homolog A), MIHB and MIHC have been described. These three mammalian inhibitor of apoptosis proteins (IAPs) are designated XIAP, c-IAP1 and c-IAP2, respectively. XIAP, c-IAP1 and c-IAP2 share an N-terminal baculovirus IAP repeat (BIR) motif and a C-terminal RING finger. Although c-IAP1 and c-IAP2 do not directly associate with the TNF receptor (TNF-R), they efficiently block TNF-mediated apoptosis through their interaction with the downstream TNF-R effectors, TRAF1 and TRAF2. The interaction between the TRAF1/TRAF2 heterocomplexes and c-IAPs is dependent on a functional BIR motif.
Host	Rabbit
Immunogen	Recombinant full length Human BIRC2.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q13490
Uniprot	Q13490
Weight	70 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: BIRC2 polyclonal antibody detects endogenous levels of BIRC2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303970	BS6088	50µl	$234.89		Add to Cart
BHA11303970	BS6088	100µl	$368.22		Add to Cart

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