JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-Bcr Antibody Picoband®

SKU : BHA21000894

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	PB9988, PB9988-10ug, PB9988-Biotin, PB9988-Cy3, PB9988-Dylight488, PB9988-Dylight550, PB9988-Dylight594, PB9988-FITC, PB9988-HRP, PB9988-APC, PB9988-PE, PB9988-iFluor647, PB9988-carrier-free
Alternative Names	Breakpoint cluster region protein
Background	The breakpoint cluster region protein (BCR) is a protein that in humans is encoded by the BCR gene. A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Bcr Antibody Picoband® catalog # PB9988. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity. .
Host	Rabbit
Immunogen Region	E.coli-derived human Bcr recombinant protein (Position: M1-A100). Human Bcr shares 94% amino acid (aa) sequence identity with mouse Bcr.
Isotype	Rabbit IgG
Molecular Weight	143 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Breakpoint cluster region protein;2.7.11.1;Renal carcinoma antigen NY-REN-26;BCR;BCR1, D22S11;
Tissue Specificity	Ubiquitous, with higher levels in heart, substantia nigra, and kidney. .
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P11274
Gene Id	613
Gene Name	BCR
Subcellular Location	Cell junction, synapse, postsynaptic cell membrane, postsynaptic density .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. "Entrez Gene: Breakpoint cluster region". 2. Puil L, Liu J, Gish G, Mbamalu G, Bowtell D, Pelicci PG, Arlinghaus R, Pawson T (February 1994). "Bcr-Abl oncoproteins bind ly to activators of the Ras signalling pathway". EMBO J. 13 (4): 76473. 3. Pendergast AM, Muller AJ, Havlik MH, Maru Y, Witte ON (July 1991). "BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner".Cell 66 (1): 16171.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000894-1	PB9988	100 ug	-	$370		Add to Cart
BHA21000894-2	PB9988-10ug	10 ug	Sample	$99		Add to Cart
BHA21000894-3	PB9988-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000894-4	PB9988-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000894-5	PB9988-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000894-6	PB9988-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000894-7	PB9988-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000894-8	PB9988-FITC	100 ug	FITC	$570		Add to Cart
BHA21000894-9	PB9988-HRP	100 ug	HRP	$570		Add to Cart
BHA21000894-10	PB9988-APC	100 ug	APC	$670		Add to Cart
BHA21000894-11	PB9988-PE	100 ug	PE	$670		Add to Cart
BHA21000894-12	PB9988-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000894-13	PB9988-carrier-free	100 ug	carrier-free	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.