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Home / Primary Antibodies / IHC Antibodies

Anti-BCAR1 Antibody BHA11300828

SKU : BHA11300828

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Mfr.No.	BS1680
Alternative Names	Breast cancer anti-estrogen resistance protein 1 ; CRK-associated substrate ; Cas scaffolding protein family member 1 ; p130cas ; BCAR1 ; CAS ; CASS1 ; CRKAS
Categories	Primary Antibodies
Chromosome Location	16q23.1
Clonality	polyclonal
Description	The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 140-180 of Human p130 Cas.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P56945
Uniprot	P56945
Weight	130 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p130 Cas (P160) polyclonal antibody detects endogenous levels of p130 Cas protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300828	BS1680	50µl	$190.44		Add to Cart
BHA11300828	BS1680	100µl	$294.44		Add to Cart

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