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Home / Primary Antibodies / IHC Antibodies

Anti-BAG4 Antibody BHA11308804

SKU : BHA11308804

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Mfr.No.	BS9179
Alternative Names	BAG 4 ; BAG family molecular chaperone regulator 4 ; BAG-4 ; BAG4 ; BAG4 ; Bcl 2 associated athanogene 4 ; Bcl-2-associated athanogene 4 ; BCL2 associated athanogene 4 ; Silencer of death domains ; SODD
Antigen	BAG4
Categories	Primary Antibodies
Chromosome Location	8p11.23
Clonality	polyclonal
Description	The cytokine TNF (tumor necrosis factor) signals through the TNF-R1 receptor to activate various cellular pathways, including apoptosis and NFkB activation. TNF binding induces receptor aggregation, resulting in the recruitment of TRADD, FADD, TRAF2 and RIP to the intracellular “death” domain of the receptor complex, which in turn activates signaling pathways including apoptosis and NFkB activation. SODD, for silencer of death domains, was found to be associated with the intracellular “death” domain of TNF-R1 in the absence of TNF stimulation. TNF treatment results in the release of SODD from TNF-R1, allowing the recruitment of TRADD and TRAF2 to the receptor complex. Thus, SODD may play a role in preventing spontaneous signaling by death-domain receptors, in the absence of ligand.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 411-460 of Human Bag-4.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O95429
Uniprot	O95429
Weight	49 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Bag-4 (V442) polyclonal antibody detects endogenous levels of Bag-4 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308804	BS9179	50µl	$190.44		Add to Cart
BHA11308804	BS9179	100µl	$294.44		Add to Cart

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