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Home / Primary Antibodies / Recombinant Antibodies

Anti-ASPH Antibody BHA11308376

SKU : BHA11308376

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Mfr.No.	BS8555
Alternative Names	Aspartyl/asparaginyl beta-hydroxylase ; Aspartate beta-hydroxylase ; ASP beta-hydroxylase ; Peptide-aspartate beta-dioxygenase ; ASPH ; BAH
Antigen	ASPH
Categories	Primary Antibodies
Chromosome Location	8q12.3
Clonality	polyclonal
Description	This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.
Host	Rabbit
Immunogen	Recombinant full length Human ASPH.
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q12797
Uniprot	Q12797
Weight	86kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: ASPH polyclonal antibody detects endogenous levels of ASPH protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308376	BS8555	50µl	$234.89		Add to Cart
BHA11308376	BS8555	100µl	$368.22		Add to Cart

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