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Home / Primary Antibodies / Monoclonal Antibodies

Anti-AREB6/ZEB1 Antibody Picoband® (monoclonal, 8B12D7)

SKU : BHA21004424

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Mfr.No.	M00548-2, M00548-2-10ug, M00548-2-Biotin, M00548-2-Cy3, M00548-2-Dylight488, M00548-2-Dylight550, M00548-2-Dylight594, M00548-2-FITC, M00548-2-HRP, M00548-2-APC, M00548-2-PE, M00548-2-iFluor647, M00548-2-carrier-free
Alternative Names	aldehyde dehydrogenase 2 family member
Background	ZEB1 (Zinc Finger E Box-Binding Homeobox 1), also called TCF8, NIL2A or DELTA-EF1, is a protein that in humans is encoded by the ZEB1 gene. Fluorescence in situ hybridization localized the ZEB1 gene to chromosome 10p11.2. Krafchak et al. (2005) demonstrated a complex (core plus secondary) binding site for TCF8 in the promoter of the COL4A3 gene, mutant in Alport syndrome and which encodes collagen type IV alpha-3. They detected expression of TCF8 in coea. Nishimura et al. (2006) found that delta-Ef1 was upregulated during differentiation in a mouse smooth muscle cell (SMC) line.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-AREB6/ZEB1 Antibody Picoband® (monoclonal, 8B12D7) catalog # M00548-2. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low de
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human AREB6/ZEB1.
Isotype	Mouse IgG2b
Molecular Weight	200 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI; ALDH2; ALDM
Tissue Specificity	Plasma, liver, kidney, heart, brain, small intestine and lung. In the plasma, associated with HDL.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P37275
Gene Id	6935
Gene Name	ZEB1
Clone No	Clone: 8B12D7
Subcellular Location	Mitochondrion matrix

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	IF, IHC, ICC, WB
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Immunofluorescence, 5 ug/ml, Human<br>

Reference	1. Krafchak, C. M., Pawar, H., Moroi, S. E., Sugar, A., Lichter, P. R., Mackey, D. A., Mian, S., Nairus, T., Elner, V., Schteingart, M. T., Downs, C. A., Kijek, T. G., and 9 others. Mutations in TCF8 cause posterior polymorphous coeal dystrophy and ectopic expression of COL4A3 by coeal endothelial cells. Am. J. Hum. Genet. 77: 694-708, 2005. <br /><br />2. Nishimura, G., Manabe, I., Tsushima, K., Fujiu, K., Oishi, Y., Imai, Y., Maemura, K., Miyagishi, M., Higashi, Y., Kondoh, H., Nagai, R. Delta-EF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation. Dev. Cell 11: 93-104, 2006.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004424-1	M00548-2	-	100 ug	$370		Add to Cart
BHA21004424-2	M00548-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21004424-3	M00548-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004424-4	M00548-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004424-5	M00548-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004424-6	M00548-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004424-7	M00548-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004424-8	M00548-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21004424-9	M00548-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21004424-10	M00548-2-APC	APC	100 ug	$670		Add to Cart
BHA21004424-11	M00548-2-PE	PE	100 ug	$670		Add to Cart
BHA21004424-12	M00548-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004424-13	M00548-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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