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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Apolipoprotein E/APOE Antibody Picoband®

SKU : BHA21000892

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Mfr.No.	PB9986, PB9986-10ug, PB9986-Biotin, PB9986-Cy3, PB9986-Dylight488, PB9986-Dylight550, PB9986-Dylight594, PB9986-FITC, PB9986-HRP, PB9986-APC, PB9986-PE, PB9986-iFluor647, PB9986-carrier-free
Alternative Names	Apolipoprotein E
Background	APOE is also known as AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Apolipoprotein E/APOE Antibody Picoband® catalog # PB9986. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Mediates the binding, intealization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. .
Host	Rabbit
Immunogen Region	E.coli-derived mouse Apolipoprotein E recombinant protein (Position: D55-Q294). Mouse Apolipoprotein E shares 75% and 94.6% amino acid (aa) sequence identity with human and rat Apolipoprotein E, respectively.
Isotype	Rabbit IgG
Molecular Weight	36 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Apolipoprotein E;Apo-E;Apoe;
Tissue Specificity	Secreted in plasma.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P08226
Gene Id	11816
Gene Name	Apoe
Subcellular Location	Secreted .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, Rat, By Heat Immunocytochemistry/Immunofluorescence, 5ug/ml, Mouse Immunofluorescence, 5ug/ml, Mouse, Rat

Reference	1. APOE epsilon variants increase risk of warfarin-related intracerebral hemorrhage.Falcone GJ, et al. Neurology, 2014 Sep 23. 2. Calabuig-Navarro MV, et al. Apolipoprotein E genotype has a modest impact on the postprandial plasma response to meals of varying fat composition in healthy men in a randomized controlled trial. J Nutr, 2014 Nov.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000892-1	PB9986	100 ug	-	$370		Add to Cart
BHA21000892-2	PB9986-10ug	10 ug	Sample	$99		Add to Cart
BHA21000892-3	PB9986-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000892-4	PB9986-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000892-5	PB9986-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000892-6	PB9986-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000892-7	PB9986-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000892-8	PB9986-FITC	100 ug	FITC	$570		Add to Cart
BHA21000892-9	PB9986-HRP	100 ug	HRP	$570		Add to Cart
BHA21000892-10	PB9986-APC	100 ug	APC	$670		Add to Cart
BHA21000892-11	PB9986-PE	100 ug	PE	$670		Add to Cart
BHA21000892-12	PB9986-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000892-13	PB9986-carrier-free	100 ug	carrier-free	$370		Add to Cart

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