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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Annexin A2/ANXA2 Antibody Picoband®

SKU : BHA21006734

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Mfr.No.	PA1348, PA1348-10ug, PA1348-Biotin, PA1348-Cy3, PA1348-Dylight488, PA1348-Dylight550, PA1348-Dylight594, PA1348-FITC, PA1348-HRP, PA1348-APC, PA1348-PE, PA1348-iFluor647, PA1348-carrier-free
Alternative Names	Annexin A2
Background	Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. The ANXA2 gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alteatively spliced transcript variants encoding different isoforms have been found for this gene. This protein is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. Richard et al. (1994) presented an integration of the physical, expression, and genetic maps of human chromosome 15. They placed the ANXA2 gene in their region IV, i.e., 15q21-q22, thus confirming the previous localization.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Annexin A2/ANXA2 Antibody catalog # PA1348. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably r
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human Annexin A2, different from the rat sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	36 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Annexin A2;Annexin II;Annexin-2;Calpactin I heavy chain;Calpactin-1 heavy chain;Chromobindin-8;Lipocortin II;Placental anticoagulant protein IV;PAP-IV;Protein I;p36;ANXA2;ANX2, ANX2L4, CAL1H, LPC2D;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P07355
Gene Name	ANXA2
Sequence	Belongs to the annexin family.
Subcellular Location	Secreted, extracellular space, extracellular matrix, basement membrane . Melanosome . In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Frozen Section), 0.5-1ug/ml, Human, Mouse, Rat, -<br>Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat<br>Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Takahashi S, Reddy SV, Chirgwin JM, Devlin R, Haipek C, Anderson J, Roodman GD (November 1994). "Cloning and identification of annexin II as an autocrine/paracrine factor that increases osteoclast formation and bone resorption". J. Biol. Chem. <br /><br />2. "Entrez Gene: ANXA2 annexin A2".<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006734-1	PA1348	-	100 ug	$370		Add to Cart
BHA21006734-2	PA1348-10ug	Sample	10 ug	$99		Add to Cart
BHA21006734-3	PA1348-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006734-4	PA1348-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006734-5	PA1348-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006734-6	PA1348-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006734-7	PA1348-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006734-8	PA1348-FITC	FITC	100 ug	$570		Add to Cart
BHA21006734-9	PA1348-HRP	HRP	100 ug	$570		Add to Cart
BHA21006734-10	PA1348-APC	APC	100 ug	$670		Add to Cart
BHA21006734-11	PA1348-PE	PE	100 ug	$670		Add to Cart
BHA21006734-12	PA1348-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006734-13	PA1348-carrier-free	carrier-free	100 ug	$370		Add to Cart

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