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Home / Primary Antibodies / IHC Antibodies

Anti-ANG Antibody BHA11303645

SKU : BHA11303645

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Mfr.No.	BS60510
Alternative Names	Angiogenin ; Ribonuclease 5 ; RNase 5 ; ANG ; RNASE5
Antigen	ANG
Categories	Primary Antibodies
Chromosome Location	14q11.2
Clonality	polyclonal
Description	Angiogenesis is defined as the process of neovascularization and formation of new blood vessels from the established micro-circulation. Angiogenin (ANG or ANG I) is a non-glycosylated polypeptide, 123 amino acids in length, whose function is central to this process. ANG I shows a high degree of homology with known ribonucleases such as pancreatic ribonuclease A, and the capacity of ANG I to induce blood vessel growth is critically dependent on its ribonucleolytic activity. ANG I is thought to be involved in the development of solid tumors, and ANG I antagonists are capable of inhibiting tumor growth. By a poorly understood mechanism, ANG I is endocytosed by subconfluent endothelial cells and translocated to the nucleus where it accumulates in the nucleolus. The ANG I receptor has not yet been identified.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human ANG
Reactivity	Human, Mouse
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P03950
Uniprot	P03950
Weight	17 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: ANG polyclonal antibody detects endogenous levels of ANG protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303645	BS60510	50µl	$190.44		Add to Cart
BHA11303645	BS60510	100µl	$294.44		Add to Cart

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