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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Amyloid-like protein 1 APLP1 Antibody Picoband®

SKU : BHA21007303

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Mfr.No.	PA2096, PA2096-10ug, PA2096-Biotin, PA2096-Cy3, PA2096-Dylight488, PA2096-Dylight550, PA2096-Dylight594, PA2096-FITC, PA2096-HRP, PA2096-APC, PA2096-PE, PA2096-iFluor647, PA2096-carrier-free
Alternative Names	Amyloid-like protein 1
Background	Amyloid-precursor-like protein 1 (APLP1) is a membrane-associated glycoprotein, whose gene is homologous to the APP gene, which has been shown to be involved in the pathogenesis of Alzheimer's disease. APLP1 is predominantly expressed in brain, particularly in the cerebral cortex postsynaptic density. The human gene has been mapped to chromosomal region 19q13.1. The gene is 11.8 kb long and contains 17 exons. APLP1 has been considered a candidate gene for CNF. All exon regions of the gene were amplified by the polymerase chain reaction and sequenced from DNA of CNF patients. No differences were observed between CNF patients and controls, suggesting that mutations in APLP1 are not involved in the etiology of CNF.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Amyloid-like protein 1 APLP1 Antibody catalog # PA2096. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interac
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human APLP1, different from the related mouse and rat sequences by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	72 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Amyloid-like protein 1;APLP;APLP-1;C30;APLP1;
Tissue Specificity	Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD). .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P51693
Gene Name	APLP1
Subcellular Location	Cell membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, Mouse, By Heat <br>Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1?Lenkkeri, U., Kestila, M., Lamerdin, J., McCready, P., Adamson, A., Olsen, A., Tryggvason, K. Structure of the human amyloid-precursor-like protein gene APLP1 at 19q13.1. Hum. Genet. 102: 192-196, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007303-1	PA2096	-	100 ug	$370		Add to Cart
BHA21007303-2	PA2096-10ug	Sample	10 ug	$99		Add to Cart
BHA21007303-3	PA2096-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007303-4	PA2096-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007303-5	PA2096-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007303-6	PA2096-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007303-7	PA2096-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007303-8	PA2096-FITC	FITC	100 ug	$570		Add to Cart
BHA21007303-9	PA2096-HRP	HRP	100 ug	$570		Add to Cart
BHA21007303-10	PA2096-APC	APC	100 ug	$670		Add to Cart
BHA21007303-11	PA2096-PE	PE	100 ug	$670		Add to Cart
BHA21007303-12	PA2096-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007303-13	PA2096-carrier-free	carrier-free	100 ug	$370		Add to Cart

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