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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Alpha 2 Antiplasmin/SERPINF2 Antibody Picoband®

SKU : BHA21004063

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Mfr.No.	A04248-2, A04248-2-10ug, A04248-2-Biotin, A04248-2-Cy3, A04248-2-Dylight488, A04248-2-Dylight550, A04248-2-Dylight594, A04248-2-FITC, A04248-2-HRP, A04248-2-APC, A04248-2-PE, A04248-2-iFluor647, A04248-2-carrier-free
Alternative Names	Fc fragment of IgE, low affinity II, receptor for (CD23)
Background	Alpha 2-antiplasmin (or alpha2-antiplasmin or plasmin inhibitor) is a serine protease inhibitor (serpin) responsible for inactivating plasmin. Plasmin is an important enzyme that participates in fibrinolysis and degradation of various other proteins. This protein is encoded by the SERPINF2 gene. This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Alpha 2 Antiplasmin/SERPINF2 Antibody Picoband® catalog # A04248-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Host	Rabbit
Immunogen Region	E.coli-derived human Alpha 2 Antiplasmin/SERPINF2 recombinant protein (Position: K461-K491).
Isotype	Rabbit IgG
Molecular Weight	65 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; CD23; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; FCER2; CD23A; CLEC4J; FCE2; IGEBF
Tissue Specificity	Highly expressed on high endothelial venules (HEV) and lamina propia venules found in the small intestine, and to a lesser extent in the colon and spleen. Very low levels of expression found in pancreas and brain. Not expressed in the thymus, prostate, ovaries, testis, heart, placenta, lung, liver, skeletal muscle, kidney or peripheral blood leukocytes.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P08697
Gene Id	5345
Gene Name	SERPINF2
Subcellular Location	Cell membrane; Also exists as a soluble excreted form, sCD23.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Bangert, K., Johnsen, A. H., Christensen, U., Thorsen, S. Different N-terminal forms of alpha-2-plasmin-inhibitor in human plasma. Biochem. J. 291: 623-625, 1993.<br /><br />2. Favier, R., Aoki, N., de Moerloose, P. Congenital alpha-2-plasmin inhibitor deficiencies: a review. Brit. J. Haemat. 114: 4-10, 2001. <br /><br />3. Hirosawa, S., Nakamura, Y., Miura, O., Sumi, Y., Aoki, N. Organization of the human alpha-2-plasmin inhibitor gene. Proc. Nat. Acad. Sci. 85: 6836-6840, 1988. Note: Erratum: Proc. Nat. Acad. Sci. 86: 1612-1613, 1989.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004063-1	A04248-2	-	100 ug	$370		Add to Cart
BHA21004063-2	A04248-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21004063-3	A04248-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004063-4	A04248-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004063-5	A04248-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004063-6	A04248-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004063-7	A04248-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004063-8	A04248-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21004063-9	A04248-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21004063-10	A04248-2-APC	APC	100 ug	$670		Add to Cart
BHA21004063-11	A04248-2-PE	PE	100 ug	$670		Add to Cart
BHA21004063-12	A04248-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004063-13	A04248-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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