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Home / Primary Antibodies / Polyclonal Antibodies

Anti-alpha 1d Adrenergic Receptor/ADRA1A Antibody Picoband®

SKU : BHA21000655

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Mfr.No.	PB9752, PB9752-10ug, PB9752-Biotin, PB9752-Cy3, PB9752-Dylight488, PB9752-Dylight550, PB9752-Dylight594, PB9752-FITC, PB9752-HRP, PB9752-APC, PB9752-PE, PB9752-iFluor647, PB9752-carrier-free
Alternative Names	Alpha-1A adrenergic receptor
Background	ADRA1A, also known as alpha-1A adrenergic receptor, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it. This gene is mapped to 8p21.2. Alpha-1-adrenergic receptors are G protein-coupled transmembrane receptors that mediate actions in the sympathetic nervous system through the binding of the catecholamines, epinephrine and norepinephrine. It has been found that ADRA1A transcripts in heart, brain, liver, and prostate. ADRA1A is the predominant ADRA1 subtype in liver and heart, and it can mediate the contraction of prostate smooth muscle.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-alpha 1d Adrenergic Receptor/ADRA1A Antibody Picoband® catalog # PB9752. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G (q) and G (11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate ph
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human ADRA1A, different from the related mouse and rat sequences by four amino acids.
Isotype	Rabbit IgG
Molecular Weight	51 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Alpha-1A adrenergic receptor;Alpha-1A adrenoreceptor;Alpha-1A adrenoceptor;Alpha-1C adrenergic receptor;Alpha-adrenergic receptor 1c;ADRA1A;ADRA1C;
Tissue Specificity	Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethral and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P35348
Gene Id	148
Gene Name	ADRA1A
Subcellular Location	Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat

Reference	1. Hirasawa, A., Horie, K., Tanaka, T., Takagaki, K., Murai, M., Yano, J., Tsujimoto, G.Cloning, functional expression and tissue distribution of human cDNA for the alpha-1C-adrenergic receptor. Biochem. Biophys. Res. Commun. 195: 902-909, 1993. 2. Langer SZ (1998). "Nomenclature and state of the art on alpha1-adrenoceptors". Eur. Urol. 33 Suppl 2: 26. 3. Weinberg, D. H., Trivedi, P., Tan, C. P., Mitra, S., Perkins-Barrow, A., Borkowski, D., Strader, C. D., Bayne, M. Cloning, expression and characterization of human alpha adrenergic receptors alpha-1A, alpha-1B, and alpha-1C. Biochem. Biophys. Res. Commun. 201: 1296-1304, 1994.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000655-1	PB9752	100 ug	-	$370		Add to Cart
BHA21000655-2	PB9752-10ug	10 ug	Sample	$99		Add to Cart
BHA21000655-3	PB9752-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000655-4	PB9752-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000655-5	PB9752-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000655-6	PB9752-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000655-7	PB9752-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000655-8	PB9752-FITC	100 ug	FITC	$570		Add to Cart
BHA21000655-9	PB9752-HRP	100 ug	HRP	$570		Add to Cart
BHA21000655-10	PB9752-APC	100 ug	APC	$670		Add to Cart
BHA21000655-11	PB9752-PE	100 ug	PE	$670		Add to Cart
BHA21000655-12	PB9752-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000655-13	PB9752-carrier-free	100 ug	carrier-free	$370		Add to Cart

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