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Home / Primary Antibodies / Polyclonal Antibodies

Anti-AHA1/AHSA1 Antibody Picoband®

SKU : BHA21001485

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Mfr.No.	A05733, A05733-10ug, A05733-Biotin, A05733-Cy3, A05733-Dylight488, A05733-Dylight550, A05733-Dylight594, A05733-FITC, A05733-HRP, A05733-APC, A05733-PE, A05733-iFluor647, A05733-carrier-free
Alternative Names	activator of HSP90 ATPase activity 1
Background	Activator of 90 kDa heat shock protein ATPase homolog 1 is an enzyme that in humans is encoded by the AHSA1 gene. The Inteational Radiation Hybrid Mapping Consortium mapped the AHSA1 gene to chromosome 14. It acts as a co-chaperone of HSP90AA1. AHSA1 competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-AHA1/AHSA1 Antibody Picoband® catalog # A05733. Tested in ELISA, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for c
Host	Rabbit
Immunogen Region	E. coli-derived human AHA1 recombinant protein (Position: N21-F338).
Isotype	Rabbit IgG
Molecular Weight	40 kDa
Reactivity	Human, Monkey
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38; AHSA1; C14orf3; HSPC322
Tissue Specificity	Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	O95433
Gene Id	10598
Gene Name	AHSA1
Subcellular Location	Cytoplasm, cytosol.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Description	Weste blot, 0.25-0.5ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. "Entrez Gene: AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)".<br /><br />2. Lotz, G. P., Lin, H., Harst, A., Obermann, W. M. J. Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone. J. Biol. Chem. 278: 17228-17235, 2003.<br /><br />3. Panaretou B, Siligardi G, Meyer P, Maloney A, Sullivan JK, Singh S, Millson SH, Clarke PA, Naaby-Hansen S, Stein R, Cramer R, Mollapour M, Workman P, Piper PW, Pearl LH, Prodromou C (Dec 2002). "Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1". Mol. Cell. 10 (6): 130718.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001485-1	A05733	100 ug	-	$370		Add to Cart
BHA21001485-2	A05733-10ug	10 ug	Sample	$99		Add to Cart
BHA21001485-3	A05733-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001485-4	A05733-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001485-5	A05733-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001485-6	A05733-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001485-7	A05733-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001485-8	A05733-FITC	100 ug	FITC	$570		Add to Cart
BHA21001485-9	A05733-HRP	100 ug	HRP	$570		Add to Cart
BHA21001485-10	A05733-APC	100 ug	APC	$670		Add to Cart
BHA21001485-11	A05733-PE	100 ug	PE	$670		Add to Cart
BHA21001485-12	A05733-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001485-13	A05733-carrier-free	100 ug	carrier-free	$370		Add to Cart

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