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Home / Primary Antibodies / IHC Antibodies

Anti-ACVR1B Antibody BHA11301074

SKU : BHA11301074

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Mfr.No.	BS1988
Alternative Names	Activin receptor type-1B ; Activin receptor type IB ; ACTR-IB ; Activin receptor-like kinase 4 ; ALK-4 ; Serine/threonine-protein kinase receptor R2 ; SKR2 ; ACVR1B ; ACVRLK4 ; ALK4
Antigen	ACVR1B
Categories	Primary Antibodies
Chromosome Location	12q13.13
Clonality	polyclonal
Description	Members of the transforming growth factor β superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho genesis in a dose dependent fashion.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 100-150 of Human ACTR-IB.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P36896
Uniprot	P36896
Weight	56 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: ACTR-IB (G111) polyclonal antibody detects endogenous levels of ACTR-IB protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IF

Description

IHC ; IF

Dilution

IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301074	BS1988	50µl	$190.44		Add to Cart
BHA11301074	BS1988	100µl	$294.44		Add to Cart

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