This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inbo error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009] Annotation information: Note: ACAT1 (GeneID 38) and SOAT1 (GeneID 6646) loci share the ACAT1 symbol/alias in common. ACAT1 is widely used alteative name for acyl-Coenzyme A: cholesterol acyltransferase 1 (SOAT1) conflicting with the official symbol for acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) (ACAT1). [04 Jun 2007]
Host
Mouse
Immunogen
N-terminal 104 amino acids of human ACAT1 protein.
Isotype
IgG
Quantity
100 µg
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Shipping Condition
Ice Packs
Antigen
ACAT1
Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Concentration
100µg/100ul
Description
Specificity: Recognize specifically human ACAT1 and other species not tested.
Format
Liquid
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB, ELISA
Description
Weste Blot (1:1000) and ELISA (1:2000 ~ 5000)., WB ; ELISA