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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ABCB4 Antibody Picoband®

SKU : BHA21000167

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Mfr.No.	PB9275, PB9275-10ug, PB9275-Biotin, PB9275-Cy3, PB9275-Dylight488, PB9275-Dylight550, PB9275-Dylight594, PB9275-FITC, PB9275-HRP, PB9275-APC, PB9275-PE, PB9275-iFluor647, PB9275-carrier-free
Alternative Names	Multidrug resistance protein 3
Background	Adenosine triphosphate-binding cassette subfamily B, member 4 (ABCB4), also called MDR3, is a protein that in humans is encoded by the ABCB4 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. The ABCB4 gene contains 28 exons and 27 of these contain coding sequences for the two homologous halves of the protein that correlate with functional domains. ABCB4 gene mutations represent a genetic factor involved in this peculiar form of cholesterol gallstone disease in adults.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-ABCB4 Antibody Picoband® catalog # PB9275. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency. Not capable of conferring drug resistance. Mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyt
Host	Rabbit
Immunogen Region	E.coli-derived human ABCB4 recombinant protein (Position: A601-A720). Human ABCB4 shares 79% amino acid (aa) sequence identity with both mouse and rat ABCB4.
Isotype	Rabbit IgG
Molecular Weight	150 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Multidrug resistance protein 3;3.6.3.44;ATP-binding cassette sub-family B member 4;P-glycoprotein 3;ABCB4;MDR3, PGY3;
Tissue Specificity	Plasma. Expressed in liver. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	P21439
Gene Id	5244
Gene Name	ABCB4
Sequence	Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Subcellular Location	Cell membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, By Heat Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. Lincke, C. R., Smit, J. J., van der Velde Koerts, T., Borst, P. Structure of the human MDR3 gene and physical mapping of the human MDR locus. J. Biol. Chem. 266: 5303-5310, 1991. 2. Rosmorduc, O., Hermelin, B., Poupon, R. MDR3 gene defect in adults with symptomatic intrahepatic and gallbladder cholesterol cholelithiasis. Gastroenterology 120: 1459-1467, 2001.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000167-1	PB9275	100 ug	-	$370		Add to Cart
BHA21000167-2	PB9275-10ug	10 ug	Sample	$99		Add to Cart
BHA21000167-3	PB9275-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000167-4	PB9275-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000167-5	PB9275-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000167-6	PB9275-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000167-7	PB9275-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000167-8	PB9275-FITC	100 ug	FITC	$570		Add to Cart
BHA21000167-9	PB9275-HRP	100 ug	HRP	$570		Add to Cart
BHA21000167-10	PB9275-APC	100 ug	APC	$670		Add to Cart
BHA21000167-11	PB9275-PE	100 ug	PE	$670		Add to Cart
BHA21000167-12	PB9275-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000167-13	PB9275-carrier-free	100 ug	carrier-free	$370		Add to Cart

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