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Home / Primary Antibodies

Angiotensin II Type 1 Receptor Antibody / AGTR1 / AT1R (F54336)

SKU : BHA17102809

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Mfr.No.	F54336, F54336-0.08ML, F54336-0.4ML
Clonality	Polyclonal
Description	Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. (provided by RefSeq).
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 211-240 from the human protein was used as the immunogen for the Angiotensin II Type 1 Receptor antibody.
Isotype	Ig
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No

Uniprot	P30556

Format	Purified
Purification	Antigen affinity purified
Storage	Aliquot the Angiotensin II Type 1 Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	IHC-P, WB, FACS, IF
Dilution	Immunohistochemistry (FFPE): 1:25,Weste blot: 1:500-1:2000,Flow cytometry: 1:25 (1x10e6 cells),Immunofluorescence: 1:25

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17102809-1	F54336-0.08ML	0.08ml	$165		Add to Cart
BHA17102809-2	F54336-0.4ML	0.4ml	$379		Add to Cart

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