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Home / Primary Antibodies

Androgen Receptor Antibody (RQ5317)

SKU : BHA17110000

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Mfr.No.	RQ5317
Clonality	Monoclonal
Description	The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alteative splicing results in multiple transcript variants encoding different isoforms. (RefSeq)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human Androgen Receptor was used as the immunogen for the Androgen Receptor antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P10275
Clone No	HD-1

Format	Purified
Purification	Affinity purified
Storage	Store the Androgen Receptor antibody at -20°C.

Applications	WB
Dilution	Weste blot: 1:500-1:2000

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110000	RQ5317	100ul	$419		Add to Cart

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