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Home / Primary Antibodies

Androgen Receptor Antibody (F40398)

SKU : BHA17100281

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NSJ Bioreagents

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Mfr.No.	F40398, F40398-0.08ML, F40398-0.4ML
Clonality	Monoclonal
Description	Androgen receptor (ANDR) has 3 major functional domains: the N-terminal domain, DNA-binding domain, and an androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. The gene for this protein contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of the protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations are also associated with complete androgen insensitivity (CAIS). PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor; sumoylation of AR represses AR-dependent transcription.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Mouse
Immunogen Region	Purified His-tagged protein fragment was used to produced this monoclonal anti-Androgen Receptor antibody.
Isotype	IgA
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P10275
Clone No	549CT16.1.4

Format	Purified
Purification	Purified
Storage	Aliquot the anti-Androgen Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Dilution	Weste blot: 1:100-1:250

Product Manual	Data Sheet

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17100281-1	F40398-0.08ML	0.08ml	$165		Add to Cart
BHA17100281-2	F40398-0.4ML	0.4ml	$379		Add to Cart

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