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Home / Primary Antibodies

ANAPC5 Antibody

SKU : BHA10558840

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA137607
Alternative Names	ANAPC5; Anaphase-promoting complex subunit 5; ANC5; Similar to anaphase-promoting complex subunit 5;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.Yu H., Science 279:1219-1222(1998).Bechtel S., BMC Genomics 8:399-399(2007).Kraft C., EMBO J. 22:6598-6609(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human ANAPC5.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Yu H., Science 279:1219-1222(1998). Bechtel S., BMC Genomics 8:399-399(2007). Kraft C., EMBO J. 22:6598-6609(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ANAPC5 protein.

Uniprot	Q9UJX4
Gene Id	51433
Database Links	HGNC:15713 OMIM:606948 KEGG:hsa:51433 STRING:9606.ENSP00000261819 UniGene:Hs.7101
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins
Pathway	Cell cycle Ubiquitin mediated proteolysis IL-17 signaling pathway
Protein Families	APC5 family
Weight	72,526 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558840	CSB-PA137607	100ul	$297		Add to Cart

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