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Home / Antibodies

AMACR / p504S Antibody (Prostate Cancer Marker) (V3990SAF)

SKU : BHA17125813

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NSJ Bioreagents

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Mfr.No.	V3990SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	The AMACR gene encodes the racemase Alpha-methylacyl-CoA. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alteatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. (RefSeq)
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A portion of amino acids 297-394 was used as the immunogen for the AMACR antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the AMACR antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Uniprot	Q9UHK6

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the AMACR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB, IHC-P
Description	Weste blot: 0.5-1ug/ml,IHC (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125813	V3990SAF-100UG	100 ug	$499		Add to Cart

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