This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An E. coli-derived mouse protein (amino acids A2-S496) was used as the immunogen for the Alanine aminotransferase 1 antibody.
Isotype
Rabbit IgG
Species Reactivity
Mouse, Rat
Note
Optimal dilution of the Alanine aminotransferase 1 antibody should be determined by the researcher.
Uniprot
Q8QZR5
Format
Antigen affinity purified
Purity
Affinity purified
Storage
After reconstitution, the Alanine aminotransferase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.