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Home / Primary Antibodies

AKT Antibody

SKU : BHA17102407

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NSJ Bioreagents

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Mfr.No.	F53789
Clonality	Monoclonal
Description	AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. AKT plays a role as key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I.
Formulation	In ascites with 0.09% sodium azide
Host	Mouse
Immunogen Region	This AKT antibody was produced from mice immunized with a KLH conjugated synthetic peptide selected from the 430-460 region of human AKT1.
Isotype	IgG1
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P31749
Clone No	960CT4.5.1

Format	Ascites
Purification	Ascites
Storage	Aliquot the AKT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Dilution	Western blot: 1:5000

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17102407	F53789	0.1 ml	$389		Add to Cart

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