A-kinase anchor protein 17A; 721P; B-lymphocyte antigen; Protein XE7; Protein kinase A-anchoring protein 17A
Categories
Primary Antibodies
Clonality
polyclonal
Description
Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.Ellison J.W., Hum. Mol. Genet. 1:691-696(1992).Voland J.R., Proc. Natl. Acad. Sci. U.S.A. 89:10425-10429(1992).Ross M.T., Nature 434:325-337(2005).
Host
Rabbit
Immunogen
Synthesized peptide derived from C-terminal of Human SFRS17A.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.
Ellison J.W., Hum. Mol. Genet. 1:691-696(1992). Voland J.R., Proc. Natl. Acad. Sci. U.S.A. 89:10425-10429(1992). Ross M.T., Nature 434:325-337(2005).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total SFRS17A protein.
Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.
Tissue Specificity
Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B-cells and placenta. Expressed in all cell lines tested including Jurkat-TAg, U-937 and HEK293 cells.
Weight
51,409 Da
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.