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Home / Antibodies

AGO3 Antibody / Argonaute-3 / eIF2C3 (V9391SAF)

SKU : BHA17123286

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NSJ Bioreagents

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Mfr.No.	V9391SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	This antigen is involved in binding and translation repression of short RNAs. This antigen is also known as Argonaute RISC catalytic component 3. Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5-flanking sequences to the region of guide-target complementarity.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Recombinant full-length human AGO3 protein was used as the immunogen for the AGO3 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the AGO3 antibody should be determined by the researcher.

Uniprot	Q9H9G7

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the AGO3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	ELISA, FACS, IF
Description	ELISA (order BSA-free format for coating),Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17123286	V9391SAF-100UG	100ug	$499		Add to Cart

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