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Home / Primary Antibodies

AGBL4 Antibody

SKU : BHA10558372

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA598753
Alternative Names	ATP/GTP-binding protein-like 4; CBPC6; CCP6; cytosolic carboxypeptidase 6; EC 3.4.17.-
Categories	Primary Antibodies
Clonality	polyclonal
Description	Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5 By similarity.Ota T., Nat. Genet. 36:40-45(2004).Gregory S.G., Nature 441:315-321(2006).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CBCP6.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5 By similarity. Ota T., Nat. Genet. 36:40-45(2004). Gregory S.G., Nature 441:315-321(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CBCP6 protein.
Subcellular Location	Cytoplasm, cytosol, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole, Golgi apparatus, Cytoplasm, cytoskeleton, cilium basal body

Uniprot	Q5VU57
Gene Id	84871
Database Links	HGNC:25892 OMIM:616476 KEGG:hsa:84871 STRING:9606.ENSP00000360905 UniGene:Hs.551844
Function	Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
Protein Families	Peptidase M14 family
Weight	62 kDa

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558372	CSB-PA598753	100ul	$297		Add to Cart

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