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Home / Primary Antibodies / Monoclonal Antibodies

AF/LE Purified Anti-Mouse CD115 Antibody[AFS98]

SKU : BHA10325456

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F11070
Background	CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
Clonality	Monoclonal
Host	Rat
Immunogen	0
Isotype	Rat IgG2a, kappa
Reactivity	Mouse

Clone No	AFS98
Research Area	Cardiovascular, Immunology, Signal Transduction

Buffer	0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration	0.5 mg/mL
Storage	Store at 2~8°C. Do not freeze.

Applications	Block, Depletion, Neut, FCM, WB

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10325456	E-AB-F11070	50?g	$95		Add to Cart
BHA10325456	E-AB-F11070	500?g	$395		Add to Cart
BHA10325456	E-AB-F11070	1mg	$595		Add to Cart

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