Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.Zamostiano R., J. Biol. Chem. 276:708-714(2001).Deloukas P., Nature 414:865-871(2001Nagase T., DNA Res. 5:277-286(1998).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ADNP.
Involvement In Disease
Helsmoortel-van der Aa syndrome (HVDAS)
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.
Zamostiano R., J. Biol. Chem. 276:708-714(2001). Deloukas P., Nature 414:865-871(2001 Nagase T., DNA Res. 5:277-286(1998).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ADNP protein.
Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.
Tissue Specificity
Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissue
Weight
123 kDa
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.