Adipophilin, also called Perilipin 2, ADRP (Adipose differentiation related protein), and PLIN2, belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material and maybe involved in development and maintenance of adipose tissue. It is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
A human partial recombinant protein was used as the immunogen for this ADRP antibody.
Isotype
Mouse IgG2b, kappa
Species Reactivity
Human
Note
Titering of the ADRP antibody may be required for optimal performance.
Format
Purified
Purity
Protein G affinity chromatography
Storage
The ADRP antibody (with azide) can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20oC or colder.
Applications
ELISA, IHC-P
Description
ELISA (order BSA/sodium azide-free format for coating),Immunohistochemistry (FFPE): 2-4ug/ml for 30 min at RT