ADH-4; alcohol dehydrogenase class 4 mu/sigma; alcohol dehydrogenase class IV mu/sigma; EC 1.1.1.1; gastric alcohol dehydrogenase
Categories
Primary Antibodies
Clonality
polyclonal
Description
Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.Satre M.A., J. Biol. Chem. 269:15606-15612(1994).Zgombic-Knight M., J. Biol. Chem. 270:4305-4311(1995).Farres J., Eur. J. Biochem. 224:549-557(1994).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ADH7.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.
Satre M.A., J. Biol. Chem. 269:15606-15612(1994). Zgombic-Knight M., J. Biol. Chem. 270:4305-4311(1995). Farres J., Eur. J. Biochem. 224:549-557(1994).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ADH7 protein.
Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.