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Home / Antibodies

ACVR1 Antibody / ALK2 (F54223)

SKU : BHA17102735

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NSJ Bioreagents

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Mfr.No.	F54223, F54223-0.08ML, F54223-0.4ML
Antigen	ACVR1
Clonality	Polyclonal
Description	Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 6-34 from the human protein was used as the immunogen for this ALK2 antibody.
Isotype	Ig
Predicted Reactivity	Human, Rat
Reactivity	Human, Rat
Recombinant	No

Uniprot	Q04771

Format	Purified
Purification	Purified
Storage	Aliquot the ALK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB
Dilution	Western blot: 1:500-1:1000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17102735-1	F54223-0.08ML	0.08ml	$165		Add to Cart
BHA17102735-2	F54223-0.4ML	0.4ml	$379		Add to Cart

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