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Home / Antibodies

ACTN2 Antibody / Alpha Actinin 2 / Sarcomeric Alpha Actinin (V7545SAF)

SKU : BHA17126667

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NSJ Bioreagents

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Mfr.No.	V7545SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Amino acids 557-692 from the human protein were used as the immunogen for this ACTN2 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the ACTN2 antibody should be determined by the researcher.

Uniprot	P35609

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the ACTN2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/actn2-antibody-actn2-3291-v7545" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17126667	V7545SAF-100UG	100 ug	$499		Add to Cart

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