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Home / Primary Antibodies

ACTH Antibody / CLIP (V8938SAF)

SKU : BHA17122973

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NSJ Bioreagents

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Mfr.No.	V8938SAF-100UG
Clonality	Recombinant Mouse Monoclonal
Description	POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Amino acids NGAEDESAEAFPLEF from human ACTH was used as the immunogen for the recombinant ACTH antibody. This sequence is from the CLIP or Corticotropin-like intermediary peptide polypeptide of ACTH.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human, Mouse and Rat (broad species reactivity predicted)
Note	Optimal dilution of the recombinant ACTH antibody should be determined by the researcher.

Uniprot	P01189

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the recombinant ACTH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122973	V8938SAF-100UG	100ug	$499		Add to Cart

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