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Home / Antibodies

ACSL6 Antibody

SKU : BHA10558465

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA634338
Alternative Names	EC 6.2.1.3; fatty-acid-coenzyme A ligase; long-chain 6; LACS 6; long-chain acyl-CoA synthetase 6
Categories	Primary Antibodies
Clonality	polyclonal
Description	Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.Malhotra K.T., Biochem. J. 344:135-143(1999).Yagasaki F., Genes Chromosomes Cancer 26:192-202(1999).Nagase T., DNA Res. 5:355-364(1998).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human ACSL6.
Involvement In Disease	A chromosomal aberration involving ACSL6 may be a cause of myelodysplastic syndrome with basophilia. Translocation t(5;12)(q31;p13) with ETV6.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. Malhotra K.T., Biochem. J. 344:135-143(1999). Yagasaki F., Genes Chromosomes Cancer 26:192-202(1999). Nagase T., DNA Res. 5:355-364(1998).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ACSL6 protein.
Subcellular Location	Mitochondrion outer membrane, Single-pass type III membrane protein, Peroxisome membrane, Single-pass type III membrane protein, Microsome membrane, Single-pass type III membrane protein, Endoplasmic reticulum membrane, Single-pass type III membrane protein

Uniprot	Q9UKU0
Gene Id	23305
Database Links	HGNC:16496 OMIM:604443 KEGG:hsa:23305 STRING:9606.ENSP00000296869 UniGene:Hs.14945
Function	Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
Pathway	PPAR signaling pathway Adipocytokine signaling pathway
Protein Families	ATP-dependent AMP-binding enzyme family
Tissue Specificity	Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain.
Weight	77 kDa

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558465	CSB-PA634338	100ul	$297		Add to Cart

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