AChR Antibody (muscarinic)

Mfr.No.	R31325
Clonality	Polyclonal
Description	Muscarinic acetylcholine receptor 1 is a muscarinic receptor. The muscarinic cholinergic receptors belong to a larger family of GPCRs. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. AChR is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids 303-317 (KMPMVDPEAQAPTKQ-human) were used as the immunogen for this muscarinic AChR antibody (100% mouse homology).
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Uniprot	P11229

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the AChR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, IHC-F, IF, ICC
Dilution	Weste blot: 0.5-1ug/ml,Immunohistochemistry (FFPE & frozen): 1-2ug/ml, Immunofluorescence/Immunocytochemistry: 2-4ug/ml