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Home / Primary Antibodies

ACACA Antibody

SKU : BHA10557633

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA934074
Alternative Names	ACC; ACAC; ACC1; ACCA; ACACAD
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Colbert C.L., Kim C.W., Moon Y.A., Henry L. Proc. Natl. Acad. Sci. U.S.A. 107:18820-18825(2010) Moreau K., Dizin E., Ray H., Luquain C., Lefai E. J. Biol. Chem. 281:3172-3181(2006)
Host	Rabbit
Immunogen	Peptide sequence around aa.78-82(S-M-S-G-L) derived from Human Acetyl CoA Carboxylase.
Involvement In Disease	Acetyl-CoA carboxylase 1 deficiency (ACACAD)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Colbert C.L., Kim C.W., Moon Y.A., Henry L. Proc. Natl. Acad. Sci. U.S.A. 107:18820-18825(2010) Moreau K., Dizin E., Ray H., Luquain C., Lefai E. J. Biol. Chem. 281:3172-3181(2006)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of total Acetyl CoA Carboxylase protein.
Subcellular Location	Cytoplasm

Uniprot	Q13085
Gene Id	31
Database Links	HGNC:84 OMIM:200350 KEGG:hsa:31 STRING:9606.ENSP00000344789 UniGene:Hs.160556
Function	Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions
Pathway	AMPK signaling Glucagon signaling pathway Insulin signaling pathway Myocardial Fatty Acid Metabolism
Tissue Specificity	Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.
Weight	265 kDa

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557633	CSB-PA934074	100ul	$297		Add to Cart

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