This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 41-68 from the human protein was used as the immunogen for this ABO antibody.
Isotype
Mouse IgM
Species Reactivity
Human
Note
Titration of the ABO antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
P16442
Format
Ascites
Purity
Ascites
Storage
Aliquot the ABO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.